Education and Experience

Ph.D., University of Georgia, 1975
Postdoctoral Research, University of Iowa, 1975 - 1978

Major Research Interests

HORMONE RESPONSIVENESS IN HUMAN BREAST CANCER - Molecular mechanisms of progestin inhibition of programmed cell death and stimulation of proliferation in human breast cancer cells.

Representative publications:

Moore, M. R., Zhou, J. L., Blankenship, K. A., Strobl J. S., Edwards D. P. and Gentry R.N. A sequence in the 5' flanking region confers progestin responsiveness on the human c-myc gene.  J. Steroid Biochem. Mol. Biol. 62: 243-252, 1997.

Moore, M. R., Conover, J. L., Franks, K. M.  Progestin effects on long-term growth, death, and bcl-xl in breast cancer cells. Biochem. Biophys. Res. Commun. 277: 650-654, 2000. 

Moore, M.R. A rationale for inhibiting progesterone-related pathways to combat breast cancer. Current Cancer Drug Targets. 4: 183-189, 2004.

Moore, M.R., Spence, J.B., Kiningham, K.K., and Dillon, J.L. Progestin inhibition of cell death in human breast cancer cell lines. J. Steroid Biochem. Mol. Biol. 98: 218-227, 2006.
 

Back To Biochemistry